1 Introduction Neurodegenerative diseases such as Alzheimers disease (AD), Parkinsons disease (PD), and multiple sclerosis (MS) are characterized by progressive nerve damage and chronic inflammation
Redox-sensitive fluorescent proteins (roFPs) have been widely used to study GSH-related redox biology 10,11
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For the body to resist these damages, it possesses a range of endogenous antioxidants, primarily enzymatic antioxidants (superoxide dismutase (SOD), glutathione peroxidase (GPX), glutathione S-transferase (GST), glutathione reductase (GR), thioredoxin reductase (TrxR), catalase (CAT), etc.), and nonenzymatic antioxidants (glutathione (GSH), bilirubin, ubiquinone, etc.) [11]